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Home Recombinant Human Proteins All GRB2 Proteins

GRB2 (NM_002086) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300469 Recombinant protein of human growth factor receptor-bound protein 2 (GRB2), transcript variant 1, 20 ug (Larger pack size?) $680 In Stock
TA302665 Goat Polyclonal Antibody against GRB2 $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200469. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:25 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayDorso-ventral axis formationFocal adhesionGap junctionMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002077 RefSeq Size: 3317 RefSeq ORF: 654
LocusID: 2885 Cytogenetic: 17q25.1  
Synonyms : ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Summary: Isoform 2 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform 2 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death. [UniProtKB/Swiss-Prot Function]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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