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Home Recombinant Human Proteins All GRB2 Proteins

GRB2 (NM_002086) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300469 Recombinant protein of human growth factor receptor-bound protein 2 (GRB2), transcript variant 1, 20 ug (Larger pack size?) 680 In Stock
TA302665 Goat Polyclonal Antibody against GRB2 $325 3-7 Days
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Also for GRB2 (NM_002086)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200469. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:25 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayDorso-ventral axis formationFocal adhesionGap junctionMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002077 RefSeq Size: 3317 RefSeq ORF: 654
LocusID: 2885 Cytogenetic: 17q24  
Synonyms : ASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Summary: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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