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Home Recombinant Human Proteins All GSK3B Proteins

GSK3B (NM_002093) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300468 Recombinant protein of human glycogen synthase kinase 3 beta (GSK3B), 20 ug (Larger pack size?) 680 In Stock
TA303846 Rabbit monoclonal antibody against GSK-3ß (C-term)(Y174) $325 In Stock
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Also for GSK3B (NM_002093)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200468. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:47.9 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: ErbB signaling pathwayChemokine signaling pathwayCell cycleWnt signaling pathwayHedgehog signaling pathwayAxon guidanceMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002084 RefSeq Size: 1639 RefSeq ORF: 1302
LocusID: 2932 Cytogenetic: 3q13.3  
Synonyms : GSK3beta isoform; glycogen synthase kinase-3 beta; glycogen synthase kinase 3 beta
Summary: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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