Promotion ends on May 1st.
Also for PRKCZ (NM_001033581)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200438
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||46.4 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Protein KinaseDruggable Genome
||Chemokine signaling pathwayEndocytosisTight junctionInsulin signaling pathwayType II diabetes mellitus
||RefSeq Size: 2147
||RefSeq ORF: 1230|
|Synonyms : PKC-ZETA; PKC2|
|Summary: Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |
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for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich