Promotion ends on May 1st.
Also for MCM3 (NM_002388)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200208
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||90.8 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Stem cell - PluripotencyTranscription FactorsDruggable Genome
||DNA replicationCell cycle
||RefSeq Size: 3143
||RefSeq ORF: 2427|
|Synonyms : HCC5; P1-MCM3; P1.h; RLFB|
|Summary: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]. |
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact firstname.lastname@example.org
for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich