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Home Recombinant Human Proteins All DHFR Proteins

DHFR (NM_000791) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300089 Recombinant protein of human dihydrofolate reductase (DHFR), 20 µg (Larger pack size?) 680 In Stock
TA500543 anti-DHFR (Dihydrofolate reductase) mouse monoclonal antibody, clone 6G7 $379 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200089. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:21.3 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Stem cell - PluripotencyDruggable Genome
Protein Pathways: One carbon pool by folateFolate biosynthesisMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000782 RefSeq Size: 3932 RefSeq ORF: 564
LocusID: 1719 Cytogenetic: 5q11.2-q13.2  
Synonyms : DHFRP1; DYR
Summary: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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