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Home TrueClone Akt2 Clone

Akt2 (NM_007434) Mouse cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
MC216612 Akt2 (untagged) - Mouse thymoma viral proto-oncogene 2 (Akt2), transcript variant 2, (10ug), NM_007434.3, 10ug $600 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
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OriGene Data
Vector: pCMV6 Entry QM Insert Size: 1446 Restriction Site: SgfI-MluI
Sequence Data: Fully Sequenced ORF         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Explanation: NM_007434.3, NP_031460
RefSeq Size: 2957 RefSeq ORF: 1446
Synonyms : 2410016A19Rik; AW554154; PKB; PKBbeta
LocusID: 11652 Cytogenetic: 7 15.94 cM|7 B1
Gene Summary: One of the few specific substrates of AKT2 identified so far is PITX2. Phosphorylation of PITX2 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake. Phosphorylates C2CD5 on 'Ser-197' during insulin-stimulated adipocytes. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Phosphorylates CLK2 on 'Thr-343'. [UniProtKB/Swiss-Prot Function]


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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