F11r (NM_172647) Mouse Untagged Clone

CAT#: MC205758

F11r (untagged) - Mouse F11 receptor (F11r), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: F11r
• Synonyms: 9130004G24; AA638916; ESTM33; JAM; JAM-1; JAM-A; Jcam; Jcam1; Ly106
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC021876
  GTCGCGTCGGGATTGTAACTGTAATGGGCACCGAGGGGAAAGCCGGGAGGAAACTGTTGTTTCTCTTCAC GTCTATGATCCTGGGCTCTTTGGTACAAGGCAAGGGTTCGGTGTACACTGCTCAATCTGACGTCCAGGTT CCCGAGAACGAGTCCATCAAATTGACCTGCACCTACTCTGGCTTCTCCTCTCCCCGAGTGGAGTGGAAGT TCGTCCAAGGCAGCACAACTGCACTTGTGTGTTATAACAGCCAGATCACAGCTCCCTATGCGGACCGAGT CACCTTCTCATCCAGTGGCATCACGTTCAGTTCTGTGACCCGGAAGGACAATGGAGAGTATACTTGCATG GTCTCCGAGGAAGGTGGCCAGAACTACGGGGAGGTCAGCATCCACCTCACTGTGCTTGTACCTCCATCCA AGCCGACGATCAGTGTCCCCTCCTCTGTCACCATTGGGAACAGGGCAGTGCTGACCTGCTCAGAGCATGA TGGTTCCCCACCCTCTGAATATTCCTGGTTCAAGGACGGGATATCCATGCTTACAGCAGATGCCAAGAAA ACCCGGGCCTTCATGAATTCTTCATTCACCATTGATCCAAAGTCGGGGGATCTGATCTTTGACCCCGTGA CAGCCTTTGATAGTGGTGAATACTACTGCCAGGCCCAGAATGGGTATGGGACAGCCATGAGGTCAGAGGC TGCACACATGGATGCTGTGGAGCTGAATGTGGGGGGCATCGTGGCAGCTGTCCTGGTAACACTGATTCTC CTTGGACTCTTGATTTTTGGCGTCTGGTTTGCCTATAGCCGTGGATACTTTGAAAGAACAAAGAAAGGGA CTGCACCGGGTAAGAAGGTCATTTACAGCCAGCCCAGTACTCGAAGTGAGGGGGAATTCAAACAGACCTC GTCGTTCCTGGTGTGACCTGCTGCGGCTCCTCCGTTGTCCATTTGCCTTACTCAGGTGCTACAGGTTCCA GCCCCTGCTGGCTGTAGCTGCACAGGATGCCTTCAATGTCTTCTAGGTCCCACAGGACCCCTTGCTTTTA TTCTAGCTAGGATATAAATTTAAAAACATCATCTACTTCCCCCTCCTCTTTCCCACCCTCCCTCCTTTCC TTACCACCATTGGGTGGCCCGAGACTAATTACAAAGTTTTCGTTCCCCATTCCTATGTGGGATTGGGCAA GAGTCCTAGACTAGACAGTAATAGTGGCTGGGCTGACAGGAACCCAAACCAATACTTGGCTGTAAAGGCC TCTGAATAAGGACTTTAAGCCTAGCTCCCTGCTTTCTCCTCCCCGGATGGGGTGCCAGCTACTCTAGAGG GGGAGCTGCAGAGAGGAGGGGCTGAGGATGGTGACCTCAGGTCTCTAGTCTTCGGAGCTTCTCTTCTGTC TCCACAAAATGTGCCACTGGGATTCTCCTGGATTCAAAGTAAACTGACATGGTGTCCGTACGAGGTGGGA GAGCTCTGTTAGCTCCCAAGAGACTTGGAGTAAGAAAGATTTAAAGTGATCTAAAGAAAAGGCTGGAACT GGTGGCCATTAGTCACTCTTCATTTGGCTGGAACTACCGCACGGACCCTTTGAAGATATGTGTGGATGGA GAAGATACGAGCTTTATAGTCTTGGCTCTTTGGTGGCCTCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGTTGTAAATTGATATTGTTATATAGA AGGGCTTTCTAGCTCTTTGGCAAGGTTGTGTTTCTGTGTGTTTATATTTGACAGATGTTGCTGGAAATAA AAACTTCATTTGACAGAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_172647
• Insert Size: 903 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC021876, AAH21876
• RefSeq Size: 1851 bp
• RefSeq ORF: 903 bp
• Locus ID: 16456
• UniProt ID: O88792
• Cytogenetics: 1 79.43 cM
• Gene Summary: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11447115). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (PubMed:11447115). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (PubMed:9660867). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (By similarity). Involved in platelet activation (By similarity).[UniProtKB/Swiss-Prot Function]