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Home TrueClone Casp4 Clone

Casp4 (NM_007609) Mouse cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
MC205003 Casp4 (untagged) - Mouse caspase 4, apoptosis-related cysteine peptidase (Casp4), (10ug), BC061255, 10ug $190 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
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OriGene Data
Vector: pCMV6-Kan/Neo Insert Size: 1122 Restriction Site: SfiI-SfiI
Sequence Data: Fully Sequenced ORF         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq Explanation: BC061255, NP_031635
RefSeq Size: 1378 RefSeq ORF: 1122
Synonyms : Casp11; Caspl; ich-3
LocusID: 12363 Cytogenetic: 9 A1|9 2.46 cM
Gene Summary: This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is 'caspase 4, apoptosis-related cysteine peptidase', this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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