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Home cDNA Clone TrueORF All Akt2 ORF Clones

Akt2 (NM_001110208) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MR226761 Akt2 (Myc-DDK-tagged) - Mouse thymoma viral proto-oncogene 2 (Akt2), transcript variant 1, 10µg   
$600
In Stock
MG226761 GFP-tagged ORF clone of Mus musculus thymoma viral proto-oncogene 2 (Akt2) transcript variant 1 as transfection-ready DNA $640 2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 4 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
MG226761 GFP-tagged ORF clone of Mus musculus thymoma viral proto-oncogene 2 (Akt2) transcript variant 1 as transfection-ready DNA

$640 3 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for MR226761
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1446 bp
Predicted Protein MW: 55.7 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq Explanation: NM_001110208.1, NP_001103678 RefSeq Size: 3199 RefSeq ORF: 1446
Synonyms : 2410016A19Rik; AW554154; PKB; PKBbeta
LocusID: 11652 Cytogenetic: 7 15.94 cM|7 B1
Gene Summary: One of the few specific substrates of AKT2 identified so far is PITX2. Phosphorylation of PITX2 impairs its association with the CCND1 mRNA-stabilizing complex thus shortening the half-life of CCND1. AKT2 seems also to be the principal isoform responsible of the regulation of glucose uptake. Phosphorylates C2CD5 on 'Ser-197' during insulin-stimulated adipocytes. AKT2 is also specifically involved in skeletal muscle differentiation, one of its substrates in this process being ANKRD2. Phosphorylates CLK2 on 'Thr-343'. [UniProtKB/Swiss-Prot Function]

 

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