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Home cDNA Clone TrueORF All Ctsl ORF Clones

Ctsl (NM_009984) Mouse cDNA ORF Clone

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Cat. No. Description Price Availability  
MR221982L1 Lenti ORF clone of Ctsl (Myc-DDK-tagged) - Mouse cathepsin L (Ctsl), (10ug), 10µg   
2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 4 weeks
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TrueORF Data for MR221982L1
Vector: pLenti-C-Myc-DDK   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1005 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq Explanation: NM_009984.3, NP_034114 RefSeq Size: 1971 RefSeq ORF: 1005
Synonyms : 1190035F06Rik; Ctsl1; fs; MEP; nkt
LocusID: 13039 Cytogenetic: 13 B3|13 33.26 cM
Gene Summary: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. [provided by RefSeq, Aug 2015].


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