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Home cDNA Clone TrueORF All Sphk2 ORF Clones

Sphk2 (NM_020011) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MR209459L2 Lenti ORF clone of Sphk2 (mGFP-tagged) - Mouse sphingosine kinase 2 (Sphk2), transcript variant 2, (10ug), 10µg
$1220
5-6 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for MR209459L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1853 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_020011.3, NP_064395
RefSeq Size: 2969 RefSeq ORF: 1854
Synonyms : C76851
LocusID: 56632 Cytogenetic: 7 B4|7
Summary: This gene encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The encoded protein plays a role in maintaining cellular levels of sphingosine-1-phosphate. The gene product also enhances apoptosis in different cell types and suppresses cellular proliferation. In mast cells, the encoded protein is necessary for influx of calcium, protein kinase C activation, and cytokine production and degranulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].

 

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