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Home cDNA Clone TrueORF All Tnfrsf10b ORF Clones

Tnfrsf10b (NM_020275) Mouse cDNA ORF Clone

Specifications Citations (0) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MR205945 Tnfrsf10b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), 10µg
$380
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
MR205945L1 Lenti ORF clone of Tnfrsf10b (Myc-DDK-tagged) - Mouse tumor necrosis factor receptor superfamily, member 10b (Tnfrsf10b), (10ug)

$750 4 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for MR205945
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1146 bp
Predicted Protein MW: 117.2 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_020275.3, NP_064671
RefSeq Size: 3142 RefSeq ORF: 1146
Synonyms : DR5; KILLER; Ly98; MK; TRAILR2; TRICK2A; TRICK2B; TRICKB
LocusID: 21933 Cytogenetic: 14 D2|14
Summary: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. [UniProtKB/Swiss-Prot Function]

 

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