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Home cDNA Clone TrueORF All Abcd1 ORF Clones

Abcd1 (NM_007435) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MG210364 Abcd1 (GFP-tagged) - Mouse ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1), 10µg
$970
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for MG210364
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2283 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_007435.1, NP_031461
RefSeq Size: 3421 RefSeq ORF: 2211
Synonyms : Ald; Aldgh; ALDP
LocusID: 11666 Cytogenetic: X B|X 37.39 cM
Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in the human gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008].

 

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