Activation of the Ca2+-sensing receptor increases renal claudin-14 expression and urinary Ca2+ excretion Am J Physiol Renal Physiol, Mar 2013; 304: F761 - F769.
[Cldn14]
An SRF/miR-1 axis regulates NCX1 and Annexin A5 protein levels in the normal and failing heart Cardiovasc Res, Mar 2013; 10.1093/cvr/cvt042.
[JunD]
Betaglycan Alters NFB-TGFß2 Cross Talk to Reduce Survival of Human Granulosa Tumor Cells Mol. Endocrinol., Mar 2013; 27: 466 - 479.
[SMAD3]
Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression Carcinogenesis, Mar 2013; 34: 550 - 559.
[cathepsin B]
Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:
The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012].
