OriGene - CASR (NM_000388) 3’-UTR clone in pMirTarget

CASR (NM_000388) 3’-UTR clone in pMirTarget

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SC213879

3`UTR clone of calcium-sensing receptor (CASR) for miRNA target validation

$495.00

4 weeks *

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

OriGene TrueClone Data

Vector:	pMirTarget	Insert Size: 1321	Restriction Site: SgfI-MluI
Sequence Data:	Insert Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

RefSeq:	NM_000388.3
Synonyms :	CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; NSHPT; PCAR1
Locus ID:	846
Summary:	The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008].