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Home MicroRNA 3' UTR Clones

DHCR7 (NM_001163817) 3’-UTR clone in pMirTarget

Specifications Citations Related Products Product Documents
Cat. No. Description Price Availability  
SC211397 3`UTR clone of 7-dehydrocholesterol reductase (DHCR7) transcript variant 2 for miRNA target validation $495.00 4 weeks * Add to Shopping Cart
OriGene TrueClone Data
Vector:pMirTarget Insert Size: 957 Restriction Site: SgfI-MluI
Sequence Data:Insert Sequence
OTI Disclaimer:Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data
RefSeq:NM_001163817.1
Synonyms :SLOS
Locus ID:1717
Summary:This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Aug 2009].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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