OriGene - EPOR (NM_000121) 3’-UTR clone in pMirTarget

EPOR (NM_000121) 3’-UTR clone in pMirTarget

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Cat. No.

Description

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Availability

SC201990

3`UTR clone of erythropoietin receptor (EPOR) for miRNA target validation

$495.00

4 weeks *

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

OriGene TrueClone Data

Vector:	pMirTarget	Insert Size: 176	Restriction Site: SgfI-MluI
Sequence Data:	Insert Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data

RefSeq:	NM_000121.2
Synonyms :	EPO-R
Locus ID:	2057
Summary:	This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010].