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Home MicroRNA 3' UTR Clones

MECP2 (NM_001110792) 3’-UTR clone in pMirTarget

Specifications Citations Related Products Product Documents
Cat. No. Description Price Availability  
SC201744 3`UTR clone of methyl CpG binding protein 2 (Rett syndrome) (MECP2) transcript variant 2 for miRNA target validation $495.00 4 weeks * Add to Shopping Cart
OriGene TrueClone Data
Vector:pMirTarget Insert Size: 123 Restriction Site: SgfI-MluI
Sequence Data:Insert Sequence
OTI Disclaimer:Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Product Components:The cDNA clone is shipped in a 2-D bar-coded Matrix tube as 10 ug dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials.

Reference Data
RefSeq:NM_001110792.1
Synonyms :AUTSX3; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT
Locus ID:4204
Summary: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq, Jul 2009].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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