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Home Recombinant Human Proteins NACA Heavy-labeled protein

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NACA Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH325257 NM_001113202 NACA MS Standard C13 and N15-labeled recombinant protein (NP_001106673), 10 ug $1500 3 weeks
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Also for NACA (NM_001113202)
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:23.2 kDa
Expression TrueORF clone:RC225257 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_001106673 RefSeq Size: RefSeq ORF: 648
Synonyms : HSD48; NACA1; skNAC
LocusID: 4666 Cytogenetic: 12q23-q24.1  
Summary: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016].

 

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