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Home Recombinant Human Proteins F11R Heavy-labeled protein

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F11R Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH319217 NM_144503 F11R MS Standard C13 and N15-labeled recombinant protein (NP_653086), 10 ug $1500 3 weeks
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:33 kDa
Expression TrueORF clone:RC219217 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_653086 RefSeq Size: 3861 RefSeq ORF: 900
Synonyms : JAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1
LocusID: 50848 Cytogenetic: 1q21.2  
Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008].

 

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