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Home Recombinant Human Proteins EDARADD Heavy-labeled protein

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EDARADD Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH319198 NM_080738 EDARADD MS Standard C13 and N15-labeled recombinant protein (NP_542776), 10 ug $1500 3 weeks
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Also for EDARADD (NM_080738)
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:23.5 kDa
Expression TrueORF clone:RC219198 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_542776 RefSeq Size: 2891 RefSeq ORF: 618
Synonyms : ECTD11A; ECTD11B; ED3; EDA3
LocusID: 128178 Cytogenetic: 1q42.3  
Summary: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

 

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