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Home Recombinant Human Proteins JAM3 Heavy-labeled protein

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JAM3 Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH316073 NM_032801 JAM3 MS Standard C13 and N15-labeled recombinant protein (NP_116190), 10 ug $1500 3 weeks
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Also for JAM3 (NM_032801)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data
Expression Host:Human HEK293 cells Predicted MW:36.5 kDa
Expression TrueORF clone:RC216073 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_116190 RefSeq Size: 3675 RefSeq ORF: 1068
Synonyms : JAM-2; JAM-3; JAM-C; JAMC
LocusID: 83700 Cytogenetic: 11q25  
Summary: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011].

 

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