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Home Recombinant Human Proteins PADI1 Heavy-labeled protein

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PADI1 Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH313501 NM_013358 PADI1 MS Standard C13 and N15-labeled recombinant protein (NP_037490), 10 ug $1500 3 weeks
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:74.5 kDa
Expression TrueORF clone:RC213501 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_037490 RefSeq Size: 2711 RefSeq ORF: 1992
Synonyms : HPAD10; PAD1; PDI; PDI1
LocusID: 29943 Cytogenetic: 1p36.13  
Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008].

 

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