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OriGene & ISB Alliance to Create a SRM/MRM Standard Database for 5,000 Human Proteins

Rockville, MD/Seattle, WA ?May 11, 2010 ?OriGene and the Institute for Systems Biology (ISB), announce plans to create a proteotypic PeptideAtlas and develop an SRM/MRM mass spectrometry standard database for 5,000 human proteins (Press Release)

Dr. Leroy Hood on Proteome Project at OriGene's ASMS2010 Luncheon Dr. Leroy Hood Presentation on ASMS 2010

Dr. Wei-wu He on Development of Assays for Every Human Protein Dr. Weiwu He Presentation on ASMS 2010

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KCNE2 Mass Spec Standard

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Specifications Related Products FAQs
Cat. No. Ref. ID Description Price Shipping
PH311320 NM_172201 KCNE2 MS Standard C13 and N15-labeled recombinant protein (NP_751951), 10 ug $ 1500 3 weeks

Also for KCNE2 (NM_172201)

OriGene Data
Expression Host:Human HEK293 cells Predicted MW:14.3 kDa
Expression TrueORF clone:RC211320 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Labeling Efficiency:> 90% incorporation
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_751951 RefSeq Size: 809 RefSeq ORF: 372
Synonyms : ATFB4; LQT5; LQT6; MIRP1
LocusID: 9992 Cytogenetic: 21q22.12  
Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul

 

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