KCNE2 (NM_172201) Human Mass Spec Standard

CAT#: PH311320

KCNE2 MS Standard C13 and N15-labeled recombinant protein (NP_751951)

Product Images

Coomassie blue staining of purified KCNE2 protein (Cat# TP311320). The protein was produced from HEK293T cells transfected with KCNE2 cDNA clone (Cat# RC211320) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC211320
• Predicted MW: 14.5 kDa
• Protein Sequence:
  Sequence Link

  >RC211320 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MSTLSNFTQTLEDVFRRIFITYMDNWRQNTTAEQEALQAKVDAENFYYVILYLMVMIGMFSFIIVAILVS
  TVKSKRREHSNDPYHQYIVEDWQEKYKSQILNLEESKATIHENIGAAGFKMSP
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >0.05 µg/µL as determined by microplate BCA method
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 25 mM Tris-HCl, 100 mM glycine, pH 7.3
• Storage: Store at -80°C. Avoid repeated freeze-thaw cycles.
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_751951
• RefSeq Size: 809
• RefSeq ORF: 369
• Synonyms: ATFB4; LQT5; LQT6; MIRP1
• Locus ID: 9992
• UniProt ID: Q9Y6J6
• Cytogenetics: 21q22.11
• Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Transmembrane