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OriGene & ISB Alliance to Create a SRM/MRM Standard Database for 5,000 Human Proteins

Rockville, MD/Seattle, WA ?May 11, 2010 ?OriGene and the Institute for Systems Biology (ISB), announce plans to create a proteotypic PeptideAtlas and develop an SRM/MRM mass spectrometry standard database for 5,000 human proteins (Press Release)

Dr. Leroy Hood on Proteome Project at OriGene's ASMS2010 Luncheon Dr. Leroy Hood Presentation on ASMS 2010

Dr. Wei-wu He on Development of Assays for Every Human Protein Dr. Weiwu He Presentation on ASMS 2010

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S100A5 Mass Spec Standard

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Specifications Related Products FAQs
Cat. No. Ref. ID Description Price Shipping
PH310891 NM_002962 S100A5 MS Standard C13 and N15-labeled recombinant protein (NP_002953), 10 ug $ 1500 3 weeks

Also for S100A5 (NM_002962)

OriGene Data
Expression Host:Human HEK293 cells Predicted MW:12.6 kDa
Expression TrueORF clone:RC210891 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Labeling Efficiency:> 90% incorporation
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_002953 RefSeq Size: 710 RefSeq ORF: 333
Synonyms : S100D
LocusID: 6276 Cytogenetic: 1q21  
Summary: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008].

 

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