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OriGene & ISB Alliance to Create a SRM/MRM Standard Database for 5,000 Human Proteins

Rockville, MD/Seattle, WA ?May 11, 2010 ?OriGene and the Institute for Systems Biology (ISB), announce plans to create a proteotypic PeptideAtlas and develop an SRM/MRM mass spectrometry standard database for 5,000 human proteins (Press Release)

Dr. Leroy Hood on Proteome Project at OriGene's ASMS2010 Luncheon Dr. Leroy Hood Presentation on ASMS 2010

Dr. Wei-wu He on Development of Assays for Every Human Protein Dr. Weiwu He Presentation on ASMS 2010

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NAB2 Mass Spec Standard

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Specifications Related Products FAQs
Cat. No. Ref. ID Description Price Shipping
PH309554 NM_005967 NAB2 MS Standard C13 and N15-labeled recombinant protein (NP_005958), 10 ug $ 1500 3 weeks

Also for NAB2 (NM_005967)

OriGene Data
Expression Host:Human HEK293 cells Predicted MW:56.4 kDa
Expression TrueORF clone:RC209554 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Labeling Efficiency:> 90% incorporation
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_005958 RefSeq Size: 2725 RefSeq ORF: 1578
Synonyms : MADER
LocusID: 4665 Cytogenetic: 12q13.3  
Summary: This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

 

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