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Home Recombinant Human Proteins VCL Heavy-labeled protein

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VCL Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH304576 NM_003373 VCL MS Standard C13 and N15-labeled recombinant protein (NP_003364), 10 ug $1500 3 weeks
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Also for VCL (NM_003373)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data
Expression Host:Human HEK293 cells Predicted MW:116.5 kDa
Expression TrueORF clone:RC204576 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_003364 RefSeq Size: 5443 RefSeq ORF: 3201
Synonyms : CMD1W; CMH15; HEL114; MV; MVCL
LocusID: 7414 Cytogenetic: 10q22.2  
Summary: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].

 

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