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Home Recombinant Human Proteins TADA3 Heavy-labeled protein

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TADA3 Mass Spec Standard

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Cat. No. Ref. ID Description Price Availability
PH301082 NM_133480 TADA3 MS Standard C13 and N15-labeled recombinant protein (NP_597814), 10 ug $1500 3 weeks
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OriGene Data
Expression Host:Human HEK293 cells Predicted MW:41.2 kDa
Expression TrueORF clone:RC201082 Protein Sequence: Sequence Link
Tag:C-terminal MYC/DDK * Anti-Myc/DDK antibody Protein family:
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:> 50 ug/ml as determined by BCA
Labeling Method:Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer and Storage:100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Protein Image
*: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Reference Data
RefSeq: NP_597814 RefSeq Size: 2571 RefSeq ORF: 1110
Synonyms : ADA3; hADA3; NGG1; STAF54; TADA3L
LocusID: 10474 Cytogenetic: 3p25.3  
Summary: DNA-binding transcriptional activator proteins increase the rate of transcription by interacting with the transcriptional machinery bound to the basal promoter in conjunction with adaptor proteins, possibly by acetylation and destabilization of nucleosomes. The protein encoded by this gene is a transcriptional activator adaptor and a component of the histone acetyl transferase (HAT) coactivator complex which plays a crucial role in chromatin modulation and cell cycle progression. Along with the other components of the complex, this protein links transcriptional activators bound to specific promoters, to histone acetylation and the transcriptional machinery. The protein is also involved in the stabilization and activation of the p53 tumor suppressor protein that plays a role in the cellular response to DNA damage. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013].

 

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