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 Home TrueClone GUCY1A3 Clone

GUCY1A3 (NM_001130686) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC325830 Homo sapiens guanylate cyclase 1, soluble, alpha 3 (GUCY1A3), transcript variant 6 as transfection-ready DNA NM_001130686.1, 10ug $550 4 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
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OriGene Data
Vector:pCMV6-XL Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Purine metabolismVascular smooth muscle contractionGap junctionLong-term depression
Reference Data
RefSeq: NM_001130686.1, NP_001124158
 RefSeq Size: RefSeq ORF: 1100
Synonyms : GC-SA3; GUC1A3; GUCA3; GUCSA3; GUCY1A1
LocusID: 2982 Cytogenetic: 4q31.1
Summary: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012].

Transcript Variant: This variant (6) differs in the 5' UTR and uses an alternate splice site in the 3' coding region that results in a premature translation termination site, compared to variant 1. The encoded protein (isoform C) has a shorter and distinct C-terminus, compared to isoform A.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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