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 Home TrueClone HEPH Clone

HEPH (NM_001130860) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC325398 Homo sapiens hephaestin (HEPH), transcript variant 3 as transfection-ready DNA NM_001130860.1, 10ug $2090 6 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
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OriGene Data
Vector:pCMV6-XL Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: TransmembraneDruggable Genome
Reference Data
RefSeq: NM_001130860.1, NP_001124332
 RefSeq Size: RefSeq ORF: 3482
Synonyms : CPL
LocusID: 9843 Cytogenetic: Xq11
Summary: The protein encoded by this gene is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2008].

Transcript Variant: This variant (3) has an alternate 5' exon, which results in a downstream in-frame AUG start codon, and an alternate splice site in the 3' region, compared to variant 1. The resulting isoform (c) is shorter at the N-terminus and lacks an internal aa in the C-terminal region, compared to isoform a.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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