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Home TrueClone CCND1 Clone

CCND1 (NM_053056) Human cDNA Clone

Specifications Citations (2) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC119035 CCND1 (untagged)-Human cyclin D1 (CCND1) (10ug), NM_053056.1, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA300599 Rabbit Monoclonal Antibody against CCND1 (Clone EP272Y), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2880 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Stem cell relevant signaling - JAK/STAT signaling pathwayStem cell relevant signaling - Wnt Signaling pathwayStem cell - PluripotencyStem cell relevant signaling - DSL/Notch pathwayDruggable Genome
Protein Pathways: Cell cyclep53 signaling pathwayWnt signaling pathwayFocal adhesionJak-STAT signaling pathwayPathways in cancerMore Pathways >>
Reference Data
RefSeq: NM_053056.1, NP_444284
RefSeq Size: 4306 RefSeq ORF: 888
Synonyms : BCL1; D11S287E; PRAD1; U21B31
LocusID: 595 Cytogenetic: 11q13
Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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