PRKX (NM_005044) Human Untagged Clone

CAT#: SC116959

PRKX (untagged)-Human protein kinase, X-linked (PRKX)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PRKX
• Synonyms: PKX1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_005044 edited
  ATGGAGGCGCCCGGGCTGGCCCAGGCGGCCGCGGCGGAGAGCGACTCCCGCAAGGTGGCG
  GAGGAGACCCCCGACGGGGCGCCCGCGCTCTGCCCCAGCCCTGAGGCGCTGTCGCCGGAG
  CCGCCTGTGTACAGCCTGCAGGACTTTGACACGCTGGCCACCGTGGGCACTGGGACTTTC
  GGGCGGGTGCACCTGGTGAAGGAGAAGACAGCCAAGCATTTCTTCGCCCTCAAGGTGATG
  AGCATTCCTGACGTCATCCGCCTAAAGCAGGAGCAACACGTACACAATGAGAAGTCTGTC
  CTGAAGGAAGTCAGCCACCCGTTCCTCATCAGGCTGTTCTGGACGTGGCATGACGAGCGC
  TTCCTCTACATGCTCATGGAGTACGTGCCGGGCGGCGAGCTCTTCAGCTACCTGCGCAAC
  CGGGGGCGCTTCTCCAGCACCACGGGGCTCTTCTACTCTGCAGAGATCATCTGTGCCATC
  GAGTACCTGCACTCCAAAGAGATCGTCTACAGGGACTTGAAGCCAGAGAACATCCTGCTG
  GATAGGGATGGCCACATTAAGCTCACGGACTTTGGGTTCGCCAAGAAGCTGGTAGACAGG
  ACTTGGACCCTCTGTGGAACACCCGAGTACCTAGCCCCCGAAGTCATTCAGAGCAAGGGC
  CACGGAAGGGCCGTGGACTGGTGGGCCCTCGGCATCCTGATATTCGAGATGCTTTCGGGG
  TTTCCTCCGTTTTTTGATGACAACCCGTTTGGCATTTATCAGAAAATTCTTGCAGGCAAA
  ATAGATTTCCCCAGACATTTGGATTTCCATGTAAAAGACCTCATTAAGAAACTGCTCGTG
  GTTGACAGAACAAGGCGATTAGGAAACATGAAGAACGGGGCGAATGATGTGAAGCATCAT
  CGGTGGTTCCGCTCCGTGGACTGGGAAGCTGTTCCGCAGAGAAAACTGAAGCCTCCCATC
  GTGCCCAAGATAGCTGGTGACGGCGACACTTCCAACTTCGAAACTTACCCTGAGAATGAC
  TGGGACACAGCCGCGCCCGTGCCGCAGAAGGATTTAGAAATCTTCAAGAATTTCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005044 unedited
  TTAACGTACAAATATTTGTATACGACTCCTATAGGGCGGCCGCGATATCGCACGAGGCCC
  CACAGCGCGCACGCGGCTACCGAGCTGGAGGAGGCGGCGGGCGCGAGACCCGGAATGCGC
  AGGGCCCCCGCCTCGCCCCCCCCAGCCCGGGCCGCGGCCCCCGCCTTCCCCGCAGTCGTC
  CCGCACTCGGTGCCCGCCCCCCGAGGCCGGCGGCTGCTCCCACTCGGGGCCGTTGCTGCT
  TGTGCCGTGAGCGCCGCCCAGCCATTGTCCCCGTCGCTCCGTCAGCCGCGCCGGACCGCG
  CACCAGGAGGCGAGAGCGCGCATGGGGAGCCTCTGTTGATGCCGCCGCCGCGCCGCCCTC
  CGAGGCTGCGTCCCGGGAAGCCCGGCTCCCCGAGCGCTCCGGCCTGGCCCGGTGCCCCGG
  ACCTGAGTGCGTCCCCATGGAGGCGCCCGGGCTGGCCCAGGCGGCCGCGGCGGAGAGCGA
  CTCCCGCAAGGTGGCGGAGGAGACCCCCGACGGGGCGCCCGCGCTCTGCCCCAGCCCTGA
  GGCGCTGTCGCCGGAGCCGCCTGTGTACAGCCTGCAGGACTTTGACACGCTGGCCACCGT
  GGGCACTGGGACTTTCGGGCGGGTGCACCTGGTGAAGGGAGAGACAGCCAAGCATTTCTT
  CGCCCTCAAGGTGATGAGCATTCCTGACGTCATCCGCCTAAAGCAGGAGCAACACGTACA
  CAATGAGAAGTCTGTCCTGAAGGAAGTCAGCCACCCGTTCCTCATCAGGCTGNTCTGGAC
  GTGGCATGACGAGCGCTTTCTCTACATGCTCATGGAGTACGTGCCGGGCGGCGAGCTCTT
  CAGCTACCTGCGCAACGGGGGGCGCTTCTCCAGCACCACGGGGCTCTTCTACTCTGCAGA
  GATCATCTGTGCCATCGAGTACCTGCACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005044 unedited
  CGAGGCCGCAATTTANATCGAGTTTTTTTTTTTTTTTTTTGGGCAGGGTCTCACTCTGTC
  ACCCAGGCTGGAATGCAGTGGTGTGATCTCGGATCACTGCGGCCTGGACCTCCCCAGGCT
  CAAGTGATCCTCTCATCTCAGCCTCCTGAGTAGCTGAGACTACACTCACGTGCCACCATG
  CCCGGCTAATTTTTTTGTATTTTGTAGAGATGAGGTCTCACCACGTTTCCCAGACTGGTC
  TCCAACTCCTGGGCTCAAGCAATCCACCCACCTCAGCCTCCCAAAGTGCTGGGACTATAG
  GAACAAGCCACTGCATCCAGCTCAGATGAAATTTTTGAATGTGTCACAGAAGGTTTTTTT
  AAATACAGTACATTCCTCCAACAACTTCAATGTCATTGTAGATTCTTGGAATAAATTCGC
  TCCCATATCTTCCCCTCTTTGTTTCTTCTTTTAAAGTCTCAAGTTACCAGGTAAGAAGCA
  CTAAAGATACTGAAGGTAGACCTCCCCATGATATTTTCTTCCCCAAAACTATAAAATGCA
  TGTGAGATGATTTTTTTTAATGCATGCCACATACCCTTTAGATGTTGCCCCCGAGAAGAG
  ATTTTTGAAAAAACAAATTGAAAAATAAAAATTATAGGGCTCTGTAAAGTATGAACATTT
  ACATCACTGCACAATTTTTGTGCATCTGCCATAATGACTTCTATATATACCCCGGGCTAC
  ACACACACACACCCACTCACACACACAATTTGTGGGTATAACCGAACAAAGTCAGGTCAA
  AATTATAAACCTTAAGTCTATGACAAAAACCAGAAATCCCAGGAGGGACCCCACCCCTAA
  GGGATAGATAAAATTTACAACCCACCATTTTCAAAACCTCCTACAGGGGGAAATCCAGTG
  CCTAAAAATGCCAGTCCCGAAATTCACTGGGGCTCAACTATTTTAAN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005044
• Insert Size: 2710 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005044.1, NP_005035.1
• RefSeq Size: 6034 bp
• RefSeq ORF: 1077 bp
• Locus ID: 5613
• UniProt ID: P51817
• Cytogenetics: Xp22.33
• Domains: pkinase, S_TK_X, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Calcium signaling pathway, Chemokine signaling pathway, Dilated cardiomyopathy, Gap junction, GnRH signaling pathway, Hedgehog signaling pathway, Insulin signaling pathway, Long-term potentiation, MAPK signaling pathway, Melanogenesis, Olfactory transduction, Oocyte meiosis, Prion diseases, Progesterone-mediated oocyte maturation, Taste transduction, Vascular smooth muscle contraction, Vibrio cholerae infection, Wnt signaling pathway
• Gene Summary: This gene encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic AMP dependent protein kinases. The encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. This protein may also be involved in macrophage and granulocyte maturation. Abnormal recombination between this gene and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females. Pseudogenes of this gene are found on chromosomes X, 15 and Y. [provided by RefSeq, Feb 2010]