SERPING1 (NM_000062) Human Untagged Clone

CAT#: SC115553

SERPING1 (untagged)-Human serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 (SERPING1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SERPING1
• Synonyms: C1IN; C1INH; C1NH; HAE1; HAE2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000062, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTCCAGGCTGACCCTGCTGACCCTCCTGCTGCTGCTGCTGGCTGGGGATAGAGCCTCCTCAAATC
  CAAATGCTACCAGCTCCAGCTCCCAGGATCCAGAGAGTTTGCAAGACAGAGGCGAAGGGAAGGTCGCAAC
  AACAGTTATCTCCAAGATGCTATTCGTTGAACCCATCCTGGAGGTTTCCAGCTTGCCGACAACCAACTCA
  ACAACCAATTCAGCCACCAAAATAACAGCTAATACCACTGATGAACCCACCACACAACCCACCACAGAGC
  CCACCACCCAACCCACCATCCAACCCACCCAACCAACTACCCAGCTCCCAACAGATTCTCCTACCCAGCC
  CACTACTGGGTCCTTCTGCCCAGGACCTGTTACTCTCTGCTCTGACTTGGAGAGTCATTCAACAGAGGCC
  GTGTTGGGGGATGCTTTGGTAGATTTCTCCCTGAAGCTCTACCACGCCTTCTCAGCAATGAAGAAGGTGG
  AGACCAACATGGCCTTTTCCCCATTCAGCATCGCCAGCCTCCTTACCCAGGTCCTGCTCGGGGCTGGGGA
  GAACACCAAAACAAACCTGGAGAGCATCCTCTCTTACCCCAAGGACTTCACCTGTGTCCACCAGGCCCTG
  AAGGGCTTCACGACCAAAGGTGTCACCTCAGTCTCTCAGATCTTCCACAGCCCAGACCTGGCCATAAGGG
  ACACCTTTGTGAATGCCTCTCGGACCCTGTACAGCAGCAGCCCCAGAGTCCTAAGCAACAACAGTGACGC
  CAACTTGGAGCTCATCAACACCTGGGTGGCCAAGAACACCAACAACAAGATCAGCCGGCTGCTAGACAGT
  CTGCCCTCCGATACCCGCCTTGTCCTCCTCAATGCTATCTACCTGAGTGCCAAGTGGAAGACAACATTTG
  ATCCCAAGAAAACCAGAATGGAACCCTTTCACTTCAAAAACTCAGTTATAAAAGTGCCCATGATGAATAG
  CAAGAAGTACCCTGTGGCCCATTTCATTGACCAAACTTTGAAAGCCAAGGTGGGGCAGCTGCAGCTCTCC
  CACAATCTGAGTTTGGTGATCCTGGTACCCCAGAACCTGAAACATCGTCTTGAAGACATGGAACAGGCTC
  TCAGCCCTTCTGTTTTCAAGGCCATCATGGAGAAACTGGAGATGTCCAAGTTCCAGCCCACTCTCCTAAC
  ACTACCCCGCATCAAAGTGACGACCAGCCAGGATATGCTCTCAATCATGGAGAAATTGGAATTCTTCGAT
  TTTTCTTATGACCTTAACCTGTGTGGGCTGACAGAGGACCCAGATCTTCAGGTTTCTGCGATGCAGCACC
  AGACAGTGCTGGAACTGACAGAGACTGGGGTGGAGGCGGCTGCAGCCTCCGCCATCTCTGTGGCCCGCAC
  CCTGCTGGTCTTTGAAGTGCAGCAGCCCTTCCTCTTCGTGCTCTGGGACCAGCAGCACAAGTTCCCTGTC
  TTCATGGGGCGAGTATATGACCCCAGGGCCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000062 unedited
  TTCAGATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACGAGGGGAGTCCGCTG
  ACGTCGCCGCCCAGATGGCCTCCAGGCTGACCCTGCTGACCCTCCTGCTGCTGCTGCTGG
  CTGGGGATAGAGCCTCCTCAAATCCAAATGCTACCAGCTCCAGCTCCCAGGATCCAGAGA
  GTTTGCAAGACAGAGGCGAAGGGAAGGTCGCAACAACAGTTATCTCCAAGATGCTATTCG
  TTGAACCCATCCTGGAGGTTTCCAGCTTGCCGACAACCAACTCAACAACCAATTCAGCCA
  CCAAAATAACAGCTAATACCACTGATGAACCCACCACACAACCCACCACAGAGCCCACCA
  CCCAACCCACCATCCAACCCACCCAACCAACTACCCAGCTCCCAACAGATTCTCCTACCC
  AGCCCACTACTGGGTCCTTCTGCCCAGGACCTGTTACTCTCTGCTCTGACTTGGAGAGTC
  ATTCAACAGAGGCCGTGTTGGGGGATGCTTTGGTAGATTTCTCCCTGAAGCTCTACCACG
  CCTTCTCAGCAATGAAGAAGGTGGAGACCAACATGGCCTTTTCCCCATTCAGCATCGCCA
  GCCTCCTTACCCAGGTCCTGCTCGGGGCTGGGGAGAACACCAAAACAAACTTGGAGAGCA
  TCCTCTCTTACCCCAAGGACTTCACCTGTGTCCACCAGGCCCTGAAGGGCTTCACGACCA
  AAGGTGTCACCTCAGTCTCTCAGATCTTCCACAGCCCAGACCTGGCCATAAGGGACACCT
  TTGTGAATGCCTCTCGGACCCTGTACAGCAGCAGCCCCAGAGTCCTAAAGCACAACAGTG
  ACGCCAACTTGGAGCTCATCACACCTGGGTGGCNCNNAGACACCACNNACAGATCAGCCG
  GCTGCTAGACAGTCTGCCCTTCGATACCGNCTTGTNCTNCTCATGCTATCTACTGAGTGC
  CAGTGGAAGACACATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000062 unedited
  GACCGCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGTCTGTCAGGTTTT
  ATTTATAGAGTCTGGTGAACTTGAACTAGAGAAAGCTGCAAAAAGTGGTTTGGAGAGCAT
  GGCAGGGCCATGGAGAAGGGCTAATAGAAGCAGGTCCCTTGCCCAGACCCTCAGGGAGCC
  CTTTTGGTGGATAGCGGACACCTGAGGCAGGAGGTGGCAGGGGCCAAGTCCAGGCAGGCA
  GCAGCAGGGCTGCAACTGAGAGCTGAGGCTGGAGAGGTAGCGCTCGCCCTAACCTGATCC
  TGCAGGTCTCAGGCCCTGGGGTCATATACTCGCCCCATGAAGACAGGGAACTTGTGCTGC
  TGGTCCCAGAGCACGAAGAGGAAGGGCTGCTGCACTTCAAAGACCAGCAGGGTGCGGGCC
  ACAGAGATGGCGGAGGCTGCAGCCGCCTCCACCCCAGTCTCTGTCAGTTCCAGCACTGTC
  TGGTGCTGCATCGCAGAAACCTGAAGATCTGGGTCCTCTGTCAGCCCACCCAGGTTAAGG
  TCATAAGACCACTCGAAGAATTCCAATCTCTCCATGATTGAGACGATAACCTCGCTTGGT
  CCTCACTCTGATGCCGGGCAGTGTTAGGATAGTGCGCCTGCACCTTGCACATTTCCACTT
  TCCCCCTGATCGGCCTCGAAAACGAAGGGCTCAAAGCCCGTCTCCTGCCTCCCACAACAT
  GCTTTACGTCCCGTGGTACCCGGACTACTAACCCCTATTGCCGCCAACCCCCCTGTCCCC
  CCTCCCTTCCAAATCCGCCCCACCACGCCCTCCGACCCTCACGTCTTCTTCCCCGCCTCC
  CACACCCCCCCTTCACCGACGCCTCCCCCCCCCTCCTCCCACATCGCCCACCCCCCTGCA
  CTCCTCCCCTCCCCCCGCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000062
• Insert Size: 1820 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000062.2, NP_000053.2
• RefSeq Size: 1984 bp
• RefSeq ORF: 1503 bp
• Locus ID: 710
• UniProt ID: P05155
• Cytogenetics: 11q12.1
• Domains: SERPIN
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades
• Gene Summary: This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020]
  Transcript Variant: This variant (1) represents the longer transcript.