CTNNA3 (NM_013266) Human Untagged Clone

CAT#: SC115321

CTNNA3 (untagged)-Human catenin (cadherin-associated protein), alpha 3 (CTNNA3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CTNNA3
• Synonyms: ARVD13; VR22
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_013266, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCAGCTGAAACACCAATCACATTGAATATCGATCCTCAGGATCTGCAGGTCCAAACATTCACCGTGG
  AGAAGCTACTGGAGCCTCTCATAATCCAGGTTACCACACTTGTAAACTGTCCCCAGAACCCTTCCAGCAG
  GAAAAAAGGACGTTCGAAAAGAGCCAGTGTCCTTCTAGCTTCTGTGGAGGAAGCAACTTGGAATTTATTA
  GACAAGGGAGAGAAGATTGCCCAGGAAGCTACAGTTTTAAAGGATGAGCTTACGGCTTCACTTGAGGAAG
  TTCGCAAAGAAAGTGAAGCTCTGAAAGTATCAGCTGAGAGATTTACAGATGACCCCTGTTTTCTCCCAAA
  AAGGGAGGCTGTGGTTCAAGCTGCCCGTGCCTTGCTGGCTGCGGTGACGAGACTCCTTATCCTTGCGGAC
  ATGATTGATGTCATGTGCCTCTTGCAACATGTGTCAGCTTTTCAAAGGACATTTGAGTCTCTCAAAAATG
  TTGCCAACAAATCTGACCTCCAGAAAACCTACCAGAAGCTTGGGAAGGAGCTGGAAAATTTGGATTATTT
  AGCCTTCAAACGTCAGCAGGACTTAAAATCTCCAAATCAGAGAGATGAAATTGCAGGAGCCCGAGCTTCA
  CTGAAGGAGAACTCTCCCCTCTTGCATTCAATTTGTTCAGCTTGTTTGGAGCATTCTGATGTTGCTTCCC
  TCAAAGCAAGCAAGGACACAGTTTGTGAAGAAATTCAGAATGCTCTCAATGTAATTTCAAATGCTTCACA
  AGGGATCCAGAATATGACAACCCCACCAGAACCTCAGGCAGCAACCCTGGGAAGTGCCCTTGATGAGCTG
  GAGAATTTAATTGTCCTGAATCCACTCACAGTAACTGAGGAGGAAATACGACCATCACTAGAGAAACGCC
  TTGAAGCCATTATCAGTGGGGCTGCTCTGCTGGCGGATTCTTCATGTACGAGGGACTTACACCGAGAGCG
  GATTATCGCAGAATGCAACGCCATTCGCCAGGCTCTTCAGGATCTGCTTTCAGAGTACATGAACAACGCT
  GGAAAAAAAGAAAGGAGTAATACCCTGAATATTGCTTTAGACAACATGTGTAAGAAGACAAGAGACCTTC
  GCAGACAGCTCCGCAAGGCTATTATAGATCATGTGTCAGACTCTTTCCTGGATACGACAGTCCCTCTTTT
  GGTTCTCATTGAAGCTGCTAAGAATGGCCGGGAAAAGGAAATAAAAGAATATGCTGCGATATTTCATGAA
  CACACCAGCAGGCTTGTAGAGGTGGCAAATCTTGCTTGTTCCATGTCAACAAATGAAGATGGAATTAAAA
  TTGTCAAAATTGCAGCCAATCATTTGGAAACCTTGTGTCCACAGATTATTAATGCTGCACTTGCTTTGGC
  TGCAAGACCCAAAAGTCAAGCGGTCAAAAACACCATGGAAATGTACAAGCGTACATGGGAGAATCATATA
  CATGTCCTCACTGAAGCCGTAGATGACATTACAAGCATTGATGACTTCCTTGCTGTATCTGAAAGCCATA
  TCTTGGAAGATGTCAACAAGTGTATCATAGCCTTAAGAGACCAGGATGCTGATAATTTAGACCGTGCTGC
  GGGTGCTATCAGAGGCCGGGCAGCAAGAGTTGCTCACATCGTCACGGGTGAAATGGACAGTTACGAGCCA
  GGGGCTTACACGGAAGGTGTAATGAGAAATGTTAACTTCCTTACAAGTACTGTAATTCCTGAATTTGTAA
  CACAAGTGAATGTTGCCTTGGAAGCCTTAAGCAAAAGCTCATTGAATGTGTTGGATGATAATCAATTTGT
  GGACATCTCAAAGAAGATCTATGATACAATTCATGATATCAGATGTTCAGTCATGATGATTCGGACCCCA
  GAGGAACTGGAGGATGTTTCTGACCTTGAAGAGGAACACGAGGTCCGCAGTCACACCAGCATTCAGACCG
  AAGGGAAAACTGATAGGGCTAAGATGACTCAACTGCCTGAGGCAGAAAAAGAAAAGATTGCTGAGCAAGT
  TGCTGATTTCAAGAAAGTAAAGAGTAAGCTGGATGCTGAGATTGAGATATGGGATGATACAAGCAACGAC
  ATCATTGTTCTGGCCAAGAACATGTGTATGATCATGATGGAGATGACAGACTTCACTAGGGGCAAAGGAC
  CACTAAAGCATACAACTGATGTGATCTATGCAGCGAAAATGATATCAGAATCAGGATCAAGGATGGATGT
  CCTTGCTCGGCAGATTGCTAATCAGTGCCCAGATCCATCTTGTAAACAGGACTTGTTGGCCTACCTGGAA
  CAGATTAAGTTCTACTCCCACCAACTGAAAATCTGCAGTCAAGTTAAAGCTGAGATCCAGAACCTGGGAG
  GAGAGCTCATCATGTCAGCTTTGGACAGTGTCACATCCCTGATCCAAGCAGCCAAAAATTTAATGAATGC
  TGTAGTGCAAACAGTGAAAATGTCTTACATTGCCTCAACCAAGATCATCCGAATCCAGAGTCCTGCTGGG
  CCCCGGCACCCAGTTGTGATGTGGAGAATGAAGGCTCCTGCAAAAAAACCCTTGATTAAAAGAGAGAAGC
  CAGAGGAAACGTGTGCAGCTGTCAGACGAGGCTCAGCAAAGAAAAAAATCCATCCATTGCAAGTCATGAG
  TGAATTTAGAGGAAGACAAATCTACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013266 unedited
  TCTTACACCCGCCCGTTGCCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA
  GCAGAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGC
  GAATTCGGCACCAGGGAAGGCAACTCGACCTTTGGAAGCCTCTATGTTGTGACTCCACTT
  GATAAGGCAGCATGTCAGCTGAAACACCAATCACATTGAATATCGATCCTCAGGATCTGC
  AGGTCCAAACATTCACCGTGGAGAAGCTACTGGAGCCTCTCATAATCCAGGTTACCACAC
  TTGTAAACTGTCCCCAGAACCCTTCCAGCAGGAAAAAAGGACGTTCGAAAAGAGCCAGTG
  TCCTTCTAGCTTCTGTGGAGGAAGCAACTTGGAATTTATTAGACAAGGGAGAGAAGATTG
  CCCAGGAAGCTACAGTTTTAAAGGATGAGCTTACGGCTTCACTTGAGGAAGTTCGCAAAG
  AAAGTGAAGCTCTGAAAGTATCAGCTGAGAGATTTACAGATGACCCCTGTTTTCTCCCAA
  AAAGGGAGGCTGTGGTTCAAGCTGCCCGTGCCTTGCTGGCTGCGGTGACGAGACTCCTTA
  TCCTTGCGGACATGATTGATGTCATGTGCCTCTTGNCACATGTGTCAGCTTTTCAAGGAC
  ATTTGAGTCTCTCAAAATGTTGCCACAAATCTGACCTCCAGAAACCTACCAGAGCTTGGG
  AAGAGCTGGAAAATTGGATTATTTAGCCTTCAACGTCAGCAGGACTTAAAATCTCCCAAT
  CAGAAAGATGAATTTGCAGGAGCCCCGAGCTCCACTGGAAGAGGAACTTTCCCCTCTTGG
  CATTCAATTTGTTCCAACTTGTTTGGGAGCATTTCTGATGGTGGCTTCCCTAAAAACAGC
  AAGAACACATTTTGGAAAAAATTCAAAATGCTTTCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013266 unedited
  TGGCTTTCATTTATAAGAACGTTTTAAAATCACTCCAGCTTCATTGCCATTAACTGCTTC
  ATAGTTCAATGGTACAGTTCATGCAGTTATATTTTACTCAACGTCAAAAGGTTTTTCAAA
  CTGCCATTTTCCTTTTAATTACAATTGCAAGCTGATAAAAATGTATTTTTATGTTTGTAA
  AAATAGGGTCATACAGAACTTACACTTCTGTTATTATTAATATAACTCACTTTGGGATAT
  AGTTTGTTGTCTCATTTTCCCAATGGGTGATAACTCTTCTTTCACATATGTATTCGGATA
  GGCCTAACACTCAAAAGTACAGAACTCTCTAACACATTGGAAACCCAAAAGGTGAGTATG
  TGGCATCATAACTCATTGCAACCTTTATAATGTTAAGAAAGCATATTATTAATAAACAAG
  GTTGACCTTCAAAATCCAGCAAGTAGCCTAACTATTCAAATCTCACTAGGCTATCATGGA
  TATTACCCTATAAGTTGACTATGACTACATGTATTCATAGATTTAAATGGTGGTTTTTCT
  GCTATGCACGAATCCTACCTTTCTTCCTTGTTAAGTAGCCAATTACATCTAATAATACAC
  CTGTCGATTAACTGTACATTCTTTACTAACGTCTTTGTTCTATTTCACCCCAGCTTTTAT
  TTTCTTTATCGCACCATCCCCCCCACGTCCTCTTCCTCCTAATTCTCCTCCGCTCTTGGC
  TCCCCCTCTTTTTCCTTATACATTTTATCCTAATTTCCCTTTCGCCTCCATCACATCCTT
  ATTCCCCTACTAGCTTTTCCTCCTTCCCGTATTTTTTTTTCTCTCACCCGCACCTTTTTT
  TTATTTCAATCTCTCCCTCACTCCTATCAGTACCGTCACCTATTTATTTCCCCACTTTTA
  TTTATTCTCTTCNAAANACATCGCGCCTCTCCCCCATTTCTACTATTTTTCCGCTCTCCT
  CGTCTTATCCTCACCACTTCATATTTCTTACCTACG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013266
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_013266.1, NP_037398.1
• RefSeq Size: 3024 bp
• RefSeq ORF: 2688 bp
• Locus ID: 29119
• UniProt ID: Q9UI47
• Cytogenetics: 10q21.3
• Domains: Vinculin
• Protein Pathways: Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Endometrial cancer, Leukocyte transendothelial migration, Pathways in cancer, Tight junction
• Gene Summary: This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.