OriGene - MSMB (NM_138634) cDNA Clone

OriGene Data

Vector:	pCMV6-XL4	Insert Size: 500	Restriction Site: NotI-NotI
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	Secreted Protein Transmembrane
Protein Pathways:

Reference Data

RefSeq: NM_138634.1, NP_619540	RefSeq Size: 466	RefSeq ORF: 234
Synonyms : HPC13; IGBF; MSP; MSPB; PN44; PRPS; PSP; PSP-94; PSP57; PSP94
LocusID: 4477	Cytogenetic: 10q11.2
Summary: The protein encoded by this gene is a member of the immunoglobulin binding factor family. It is synthesized by the epithelial cells of the prostate gland and secreted into the seminal plasma. This protein has inhibin-like activity. It may have a role as an autocrine paracrine factor in uterine, breast and other female reproductive tissues. The expression of the encoded protein is found to be decreased in prostate cancer. Two alternatively spliced transcript variants encoding different isoforms are described for this gene. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]. Transcript Variant: This variant (PSP57) lacks an alternate coding exon compared to variant PSP94, that causes a frameshift. The resulting isoform (b) has a shorter and distinct C-terminus compared to isoform a.

TrueClone Citations:

Extreme C-terminal sites are posttranslocationally glycosylated by the STT3B isoform of the OST, Shiteshu Shrimal, Steven F. Trueman, and Reid Gilmore, J. Cell Biol., Apr 2013; 201: 81 - 95. [CD40]

Cellular glutathione plays a key role in copper uptake mediated by human copper transporter 1, Edward B. Maryon, Shannon A. Molloy, and Jack H. Kaplan, Am J Physiol Cell Physiol, Apr 2013; 304: C768 - C779. [CSS]

B-cell Maturation Antigen Is a Promising Target for Adoptive T-cell Therapy of Multiple Myeloma, Robert O. Carpenter, Moses O. Evbuomwan, Stefania Pittaluga, Jeremy J. Rose, Mark Raffeld, Shicheng Yang, Ronald E. Gress, Frances T. Hakim, and James N. Kochenderfer, Clin. Cancer Res., Apr 2013; 19: 2048 - 2060. [BCMA ]

Retinoic Acid Receptor ß Stimulates Hepatic Induction of Fibroblast Growth Factor 21 to Promote Fatty Acid Oxidation and Control Whole-body Energy Homeostasis in Mice, Yu Li, Kimberly Wong, Kenneth Walsh, Bin Gao, and Mengwei Zang, J. Biol. Chem., Apr 2013; 288: 10490 - 10504. [FGF21 ]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation, Naveen L. Pereira, Dong Lin, Linda Pelleymounter, Irene Moon, Gail Stilling, Bruce W. Eckloff, Eric D. Wieben, Margaret M. Redfield, John C. Burnett, Jr, Vivien C. Yee, and Richard M. Weinshilboum, Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

A Modified Form of Diphthamide Causes Immunotoxin Resistance in a Lymphoma Cell Line with a Deletion of the WDR85 Gene, Hui Wei, Tapan K. Bera, Alan S. Wayne, Laiman Xiang, Simona Colantonio, Oleg Chertov, and Ira Pastan, J. Biol. Chem., Apr 2013; 288: 12305 - 12312. [WDR85]

Arachidonic Acid–Induced Dilation in Human Coronary Arterioles: Convergence of Signaling Mechanisms on Endothelial TRPV4-Mediated Ca2+ Entry, Xiaodong Zheng, Natalya S. Zinkevich, Debebe Gebremedhin, Kathryn M. Gauthier, Yoshinori Nishijima, Juan Fang, David A. Wilcox, William B. Campbell, David D. Gutterman, and David X. Zhang, JAHA, Apr 2013; 2: e000080. [TRPV4 ]

Cytoglobin has bimodal: tumour suppressor and oncogene functions in lung cancer cell lines, Urszula Oleksiewicz, Triantafillos Liloglou, Kalliopi-Maria Tasopoulou, Nikoleta Daskoulidou, Julie Bryan, John R. Gosney, John K. Field, and George Xinarianos, Hum. Mol. Genet., Apr 2013; 10.1093/hmg/ddt174. [CYGB ]

Comparative Phosphoproteomic Analysis of Checkpoint Recovery Identifies New Regulators of the DNA Damage Response, Vincentius A. Halim, Mónica Alvarez-Fernández, Yan Juan Xu, Melinda Aprelia, Henk W. P. van den Toorn, Albert J. R. Heck, Shabaz Mohammed, and René H. Medema, Sci. Signal., Apr 2013; 6: rs9. [SPAG5]

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MSMB Mouse Clones

SKU	Description	Amount	Price	Shipping
MC208980	Mus musculus beta-microseminoprotein (Msmb) as transfection-ready DNA	10 ug	$380	2 weeks
MR218240	Myc-DDK-tagged ORF clone of Mus musculus beta-microseminoprotein (Msmb) as transfection-ready DNA	10 ug	$380	2 weeks
MG218240	GFP-tagged ORF clone of Mus musculus beta-microseminoprotein (Msmb) as transfection-ready DNA	10 ug	$420	3 weeks

MSMB Rat Clones

SKU	Description	Amount	Price	Shipping
RN209811	NativeORF clone of Rattus norvegicus microseminoprotein, beta (Msmb) as transfection-ready DNA	10 ug	$380	2 weeks
RR209811	Myc-DDK-tagged ORF clone of Rattus norvegicus microseminoprotein, beta (Msmb) as transfection-ready DNA	10 ug	$380	2 weeks

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MSMB (NM_138634) Human cDNA Clone

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MSMB Rat Clones

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