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Home cDNA Clone TrueORF All SMAD6 ORF Clones

SMAD6 (NM_001142861) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG227610 SMAD6 (GFP-tagged) - Human SMAD family member 6 (SMAD6), transcript variant 2, 10µg
$420
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for SMAD6 (NM_001142861)
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TrueORF Data for RG227610
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 708 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: ES Cell Differentiation/IPSCancer stem cellsTranscription FactorsDruggable Genome
Protein Pathways: TGF-beta signaling pathway

Reference Data
RefSeq: NM_001142861.1, NP_001136333
RefSeq Size: RefSeq ORF: 708
Synonyms : AOVD2; HsT17432; MADH6; MADH7
LocusID: 4091 Cytogenetic: 15q22.31
Summary: The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009].

 

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