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Home cDNA Clone TrueORF All PPARGC1B ORF Clones

PPARGC1B (NM_133263) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG224480 PPARGC1B (GFP-tagged) - Human peroxisome proliferator-activated receptor gamma, coactivator 1 beta (PPARGC1B), transcript variant 1, 10µg
$860
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for PPARGC1B (NM_133263)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
TrueORF Data for RG224480
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3072 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription FactorsDruggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_133263.2, NP_573570
RefSeq Size: 3277 RefSeq ORF: 3072
Synonyms : ERRL1; PERC; PGC-1(beta); PGC1B
LocusID: 133522 Cytogenetic: 5q32
Summary: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

 

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