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Home cDNA Clone TrueORF All PAX6 ORF Clones

PAX6 (NM_001604) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG222644 PAX6 (GFP-tagged) - Human paired box 6 (PAX6), transcript variant 2, 10µg   
$600
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 2 weeks
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Clone Modification
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TrueORF Data for RG222644
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1311 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Adult stem cellsEmbryonic stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Maturity onset diabetes of the young

Reference Data
RefSeq Explanation: NM_001604.3, NP_001595 RefSeq Size: 2781 RefSeq ORF: 1311
Synonyms : AN; AN2; D11S812E; FVH1; MGDA; WAGR
LocusID: 5080 Cytogenetic: 11p13 Domains: homeobox, PAX
Gene Summary: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015].

 

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