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Home cDNA Clone TrueORF All NUMB ORF Clones

NUMB (NM_001005744) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RG221018 NUMB (GFP-tagged) - Human numb homolog (Drosophila) (NUMB), transcript variant 2, 10µg   
$820
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TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
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0 2 weeks
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Also for NUMB (NM_001005744)
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TrueORF Data for RG221018
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1809 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Notch signaling pathway

Reference Data
RefSeq Explanation: NM_001005744.1 , NP_001005744
Synonyms: C14orf41; c14_5527; S171 RefSeq Size: 3503 RefSeq ORF: 1812
LocusID: 8650 Cytogenetic: 14q24.2-q24.3
Gene Summary: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]

 

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