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Home cDNA Clone TrueORF All P2RX3 ORF Clones

P2RX3 (NM_002559) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG218626 P2RX3 (GFP-tagged) - Human purinergic receptor P2X, ligand-gated ion channel, 3 (P2RX3), 10µg
$590
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for P2RX3 (NM_002559)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG218626
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1194 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneIon Channels: ATP ReceptorsDruggable Genome
Protein Pathways: Calcium signaling pathwayNeuroactive ligand-receptor interaction

Reference Data
RefSeq: NM_002559.2, NP_002550
RefSeq Size: 1349 RefSeq ORF: 1194
Synonyms : P2X3
LocusID: 5024 Cytogenetic: 11q12
Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008].

 

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