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 Home cDNA Clone TrueORF All ROCK2 ORF Clones

ROCK2 (NM_004850) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clone of Other Species Product Documents
Cat. No. Description Price Availability  
RG217764 GFP-tagged ORF clone of Homo sapiens Rho-associated, coiled-coil containing protein kinase 2 (ROCK2) as transfection-ready DNA, 10µg
$2070
 In Stock

$50 off anti-DDK and other anti-tag antibodies till June 30th, 2013

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Also for ROCK2 (NM_004850)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG217764
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence 		ORF Size: 4167 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: Chemokine signaling pathwayVascular smooth muscle contractionWnt signaling pathwayTGF-beta signaling pathwayAxon guidanceFocal adhesionMore Pathways >>
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_004850.3, NP_004841
 RefSeq Size: 6401 RefSeq ORF: 4167
Synonyms : ROCK-II
LocusID: 9475 Cytogenetic: 2p24 Domains: pkinase, HR1, PH, M
Summary: The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008].

 
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