OriGene - NMBR (NM_002511) Human ORF cDNA Clone

Western Blot Validated

TrueORF Data for RG213319

Vector:	pCMV6-AC-GFP Change vector?	Tag: C-terminal TurboGFP	Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Sequence Data:	ORF Nucleotide Sequence CHROMATOGRAMS Protein Sequence	ORF Size: 1173 bp Predicted Protein MW: 43.3 kDa
Restriction Sites:	SgfI-MluI Cloning Scheme for this gene Plasmid Map
OTI Annotation:	This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer:	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components:	The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families:	GPCR Transmembrane Druggable Genome
Protein Pathways:	Neuroactive ligand-receptor interaction

* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data

RefSeq: NM_002511.1, NP_002502	RefSeq Size: 1352	RefSeq ORF: 1173
Synonyms : OTTHUMP00000017317; neuromedin B receptor
LocusID: 4829	Cytogenetic: 6q21
Summary: Neuromedin B receptor binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and for gastrointestinal epithelial tissue. [provided by RefSeq, Jul 2008].

ORF Clones Citations:

Selenoprotein K is required for palmitoylation of CD36 in macrophages: implications in foam cell formation and atherogenesis, Svenja Meiler, Yvonne Baumer, Zhi Huang, Fukun W. Hoffmann, Gregory J. Fredericks, Aaron H. Rose, Robert L. Norton, Peter R. Hoffmann, and William A. Boisvert, J. Leukoc. Biol., May 2013; 93: 771 - 780. [CD36]

Trafficking of the Transcription Factor Nrf2 to Promyelocytic Leukemia-Nuclear Bodies: IMPLICATIONS FOR DEGRADATION OF NRF2 IN THE NUCLEUS, Melanie Theodore Malloy, Deneshia J. McIntosh, Treniqka S. Walters, Andrea Flores, J. Shawn Goodwin, and Ifeanyi J. Arinze, J. Biol. Chem., May 2013; 288: 14569 - 14583. [RNF4]

Cofactor Balance by Nicotinamide Nucleotide Transhydrogenase (NNT) Coordinates Reductive Carboxylation and Glucose Catabolism in the Tricarboxylic Acid (TCA) Cycle, Paulo A. Gameiro, Laura A. Laviolette, Joanne K. Kelleher, Othon Iliopoulos, and Gregory Stephanopoulos, J. Biol. Chem., May 2013; 288: 12967 - 12977. [NNT]

Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling, Hua Sun, Johannes Schlondorff, Henry N. Higgs, and Martin R. Pollak, J. Am. Soc. Nephrol., May 2013; 24: 917 - 929. [INF2]

DEK Depletion Negatively Regulates Rho/ROCK/MLC Pathway in Non–Small Cell Lung Cancer, Junying Wang, Limei Sun, Mingyue Yang, Wenting Luo, Ying Gao, Zihui Liu, Xueshan Qiu, and Enhua Wang, Journal of Histochemistry & Cytochemistry, May 2013; 10.1369/0022155413488120. [DEK]

A model of lysosomal pH regulation, Yoichi Ishida, Smita Nayak, Joseph A. Mindell, and Michael Grabe, J. Gen. Physiol., May 2013; 141: 705 - 720. [CLCN7]

A model of lysosomal pH regulation, Yoichi Ishida, Smita Nayak, Joseph A. Mindell, and Michael Grabe, J. Gen. Physiol., May 2013; 141: 705 - 720. [OSTM1]

The Serum- and Glucocorticoid-inducible Kinases SGK1 and SGK3 Regulate hERG Channel Expression via Ubiquitin Ligase Nedd4-2 and GTPase Rab11, Shawn M. Lamothe and Shetuan Zhang, J. Biol. Chem., May 2013; 288: 15075 - 15084. [SGK1]

Regulation of the Bone-restricted IFITM-like (Bril) Gene Transcription by Sp and Gli Family Members and CpG Methylation, Bahar Kasaai, Marie-Hélène Gaumond, and Pierre Moffatt, J. Biol. Chem., May 2013; 288: 13278 - 13294. [SP3]

More TrueClone Citations >>

NMBR Mouse Clones

SKU	Description	Amount	Price	Shipping
MC209043	Mus musculus neuromedin B receptor (Nmbr) as transfection-ready DNA	10 ug	$380	Next day
MR223987	Myc-DDK-tagged ORF clone of Mus musculus neuromedin B receptor (Nmbr) as transfection-ready DNA	10 ug	$380	3 weeks
MG223987	GFP-tagged ORF clone of Mus musculus neuromedin B receptor (Nmbr) as transfection-ready DNA	10 ug	$420	3 weeks

NMBR Rat Clones

SKU	Description	Amount	Price	Shipping
RN206713	NativeORF clone of Rattus norvegicus neuromedin B receptor (Nmbr) as transfection-ready DNA	10 ug	$380	Next day
RR206713	Myc-DDK-tagged ORF clone of Rattus norvegicus neuromedin B receptor (Nmbr) as transfection-ready DNA	10 ug	$380	3 weeks

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NMBR (NM_002511) Human cDNA ORF Clone

Western Blot Validated

ORF Clones Citations:

NMBR Mouse Clones

NMBR Rat Clones

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