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Home cDNA Clone TrueORF All ITGA2 ORF Clones

ITGA2 (NM_002203) Human cDNA ORF Clone

Specifications Citations (0) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG212617 ITGA2 (GFP-tagged) - Human integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), 10µg
$1870
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG212617
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3546 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Focal adhesionECM-receptor interactionHematopoietic cell lineageRegulation of actin cytoskeletonPathways in cancerSmall cell lung cancerMore Pathways >>

Reference Data
RefSeq: NM_002203.2, NP_002194
RefSeq Size: 5361 RefSeq ORF: 3546
Synonyms : BR; CD49B; GPIa; HPA-5; VLA-2; VLAA2
LocusID: 3673 Cytogenetic: 5q11.2 Domains: Int_alpha, VWA
Summary: This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

 

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