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Home cDNA Clone TrueORF All ADAM12 ORF Clones

ADAM12 (NM_003474) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG212501 ADAM12 (GFP-tagged) - Human ADAM metallopeptidase domain 12 (ADAM12), transcript variant 1, 10µg
$1440
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG212501
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2730 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinTransmembraneProteaseDruggable Genome

Reference Data
RefSeq: NM_003474.3, NP_003465
RefSeq Size: 5504 RefSeq ORF: 2730
Synonyms : ADAM12-OT1; CAR10; MCMP; MCMPMltna; MLTN; MLTNA
LocusID: 8038 Cytogenetic: 10q26 Domains: Reprolysin, DISIN, Pep_M12B_propep, ACR
Summary: This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014].

 

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