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Home cDNA Clone TrueORF All CXCL12 ORF Clones

CXCL12 (NM_000609) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG211693 CXCL12 (GFP-tagged) - Human chemokine (C-X-C motif) ligand 12 (CXCL12), transcript variant 2, 10µg
$420
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for CXCL12 (NM_000609)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG211693
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 282 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Secreted ProteinES Cell Differentiation/IPSDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionChemokine signaling pathwayAxon guidanceLeukocyte transendothelial migration

Reference Data
RefSeq: NM_000609.3, NP_000600
RefSeq Size: 3560 RefSeq ORF: 282
Synonyms : IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
LocusID: 6387 Cytogenetic: 10q11.1 Domains: IL8
Summary: This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013].

 

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