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Home cDNA Clone TrueORF All IRAK3 ORF Clones

IRAK3 (NM_007199) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG209245 IRAK3 (GFP-tagged) - Human interleukin-1 receptor-associated kinase 3 (IRAK3), transcript variant 1, 10µg
$590
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for IRAK3 (NM_007199)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG209245
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1791 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: ApoptosisNeurotrophin signaling pathway

Reference Data
RefSeq: NM_007199.1, NP_009130
RefSeq Size: 2288 RefSeq ORF: 1791
Synonyms : ASRT5; IRAKM
LocusID: 11213 Cytogenetic: 12q14.3 Domains: DEATH, pkinase, TyrKc, S_TKc
Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010].

 

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