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Home cDNA Clone TrueORF All NOS3 ORF Clones

NOS3 (NM_000603) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RG209228 NOS3 (GFP-tagged) - Human nitric oxide synthase 3 (endothelial cell) (NOS3), transcript variant 1, 10µg
$860
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RG209228
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3612 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
Protein Pathways: Arginine and proline metabolismMetabolic pathwaysCalcium signaling pathwayVEGF signaling pathwayLong-term depressionAlzheimer's diseaseMore Pathways >>

Reference Data
RefSeq: NM_000603.3, NP_000594
RefSeq Size: 4341 RefSeq ORF: 3612
Synonyms : ECNOS; eNOS
LocusID: 4846 Cytogenetic: 7q36 Domains: flavodoxin, NAD_binding_1, FAD_binding_1, NO_synthase
Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

 

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