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Home cDNA Clone TrueORF All GAA ORF Clones

GAA (NM_001079804) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG208033 GAA (GFP-tagged) - Human glucosidase, alpha; acid (GAA), transcript variant 3, 10µg   
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 4 weeks
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TrueORF Data for RG208033
Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2859 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Galactose metabolismStarch and sucrose metabolismMetabolic pathwaysLysosome

Reference Data
RefSeq Explanation: NM_001079804.1, NP_001073272 RefSeq Size: 3517 RefSeq ORF: 2859
Synonyms : LYAG
LocusID: 2548 Cytogenetic: 17q25.2-q25.3
Gene Summary: This gene encodes lysosomal alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016].


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