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Home cDNA Clone TrueORF All TBX21 ORF Clones

TBX21 (NM_013351) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG207902 TBX21 (GFP-tagged) - Human T-box 21 (TBX21), 10µg
$590
2-3 weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for TBX21 (NM_013351)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody
TrueORF Data for RG207902
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Vector:    Change vector? Tag: C-terminal
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1608 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription FactorsDruggable Genome

Reference Data
RefSeq: NM_013351.1, NP_037483
RefSeq Size: 2589 RefSeq ORF: 1608
Synonyms : T-bet; T-PET; TBET; TBLYM
LocusID: 30009 Cytogenetic: 17q21.32 Domains: TBOX
Summary: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008].

 

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