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Home cDNA Clone TrueORF All BUB1 ORF Clones

BUB1 (NM_004336) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG207013 BUB1 (GFP-tagged) - Human budding uninhibited by benzimidazoles 1 homolog (yeast) (BUB1), 10µg
$860
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for BUB1 (NM_004336)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RG207013
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3258 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: Cell cycleOocyte meiosisProgesterone-mediated oocyte maturation

Reference Data
RefSeq: NM_004336.2, NP_004327
RefSeq Size: 3486 RefSeq ORF: 3258
Synonyms : BUB1A; BUB1L; hBUB1
LocusID: 699 Cytogenetic: 2q14 Domains: pkinase, S_TKc
Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].

 

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